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Paleolithic ketogenic diet (PKD) in chronic diseases: Clinical and research data

URL: https://jevohealth.com/cgi/viewcontent.cgi?article=1115&context=journal

Journal of Evolution and Health

Publication Date: 03/2019

Summary: In the presentation we give an overview of our clinical experience and research with the paleolithic ketogenic diet (PKD), a diet that was developed by the ICMNI team. Since 2012 we have been exclusively using this approach in the treatment of a wide array of chronic conditions. We use the combined term u201dpaleolithic ketogenicu201d because the diet has its roots in both, the paleolithic and the ketogenic diet. The PKD combines the benefits of the two diets while excluding shortcomings of both diets. We have to emphasise the fact that both the classic version of the ketogenic diet and the popular version of the paleolithic diet are associated with side-effects. The side-effects of the classic ketogenic diet have been well- documented through its use over the last hundred years, whereas, the shortcomings of the popular paleolithic diet are less well-known. As examples for the side-effects, we present a patient who, after 7 years on the popular paleolithic diet, developed severe atherosclerosis, and another patient who, after following the classic ketogenic diet for 17 years, developed tophi (deposition of urate crystals in soft tissues) in multiple locations on hands and feet. Since 2012 we have been using the PKD on more than 4000 patients including those with autoimmune diseases, cancer, psychiatric and neurologic conditions. In the presentation we focus on presenting data on type 1 diabetes (T1DM) and cancer patients, as well as showing research data related to intestinal permeability measurements in healthy persons as well as in patients.

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Scientific evidence of diets for weight loss: Different macronutrient composition, intermittent fasting, and popular diets

URL: https://www.sciencedirect.com/science/article/pii/S0899900719301030#!

Journal: Nutrition

 Publication Date: 01/2020

 Summary: Review of dietary strategies fro weight loss. There is no one most effective diet to promote weight loss. In the short term, high-protein, low-carbohydrate diets and intermittent fasting are suggested to promote greater weight loss and could be adopted as a jumpstart. 

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L-carnitine ameliorated weight loss in fasting therapy: A propensity score-matched study

URL: https://www.sciencedirect.com/science/article/abs/pii/S0965229918312019

Journal: Complementary Therapies in Medicine

 Publication Date: 06/2019

 Summary: Weight and BMI decreased in both groups, but significantly more in l-carnitine group, while diastolic blood pressureand triglycerides decreased significantly more in non-l-carnitine group compared between groups, blood glucose did not differ significantly between groups. l-carnitine can boost the positive effects of fasting therapy on weight loss and maintain the stability of blood pressure.

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A High-Protein Diet With Resistance Exercise Training Improves Weight Loss and Body Composition in Overweight and Obese Patients With Type 2 Diabetes

URL: https://care.diabetesjournals.org/content/33/5/969.long

Journal: Diabetes Care

 Publication Date: 05/2010

Summary: A total of 83 men and women with type 2 diabetes were randomly assigned to an isocaloric, energy-restricted diet of either standard carbohydrate or high protein, with or without supervised RT for 16 weeks. An energy-restricted HP diet combined with RT achieved greater weight loss and more favorable changes in body composition. All treatments had similar improvements in glycemic control and CVD risk markers.

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A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women

URL: https://www.nrcresearchpress.com/doi/abs/10.1139/H07-059#.XXYblpyxXys

Journal: Applied Physiology, Nutrition, and Metabolism

 Publication Date: 06/2007

 Summary: A high-protein diet was superior to a low-fat, high-carbohydrate diet either alone or when combined with an aerobic/resistance-training program in promoting weight loss and nitrogen balance, while similarly improving body composition and risk factors for the Metabolic Syndrome in overweight and obese Canadian women.

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Protein Quantity and Quality at Levels above the RDA Improves Adult Weight Loss

URL: https://www.tandfonline.com/doi/abs/10.1080/07315724.2004.10719435

Journal: Journal of the American College of Nutrition

 Publication Date: 10/2004

 Summary: our research suggests that increased use of high quality protein at breakfast maybe important for the metabolic advantage of a higher protein diet.