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l-Carnitine and heart disease

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/29241711/

Journal: Life Science

 Publication Date: 02/2018

Summary: Exogenous carnitine administration through dietary and intravenous routes serves as a suitable protective strategy against ventricular dysfunction, ischemia-reperfusion injury, cardiac arrhythmia and toxic myocardial injury that prominently mark CVD. Additionally, carnitine reduces hypertension, hyperlipidemia, diabetic ketoacidosis, hyperglycemia, insulin-dependent diabetes mellitus, insulin resistance, obesity, etc. that enhance cardiovascular pathology. These favorable effects of l-carnitine have been evident in infants, juvenile, young, adult and aged patients of sudden and chronic heart failure as well.

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Efficacy and Safety of L-Carnitine Treatment for Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials

URL: https://www.hindawi.com/journals/bmri/2017/6274854/

Journal: BioMed Research International

 Publication Date: 04/2017

Summary: L-Carnitine treatment is effective for CHF patients in improving clinical symptoms and cardiac functions, decreasing serum levels of BNP and NT-proBNP. And it has a good tolerance.

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Efficacy and Safety of L-Carnitine Treatment for Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials

URL: https://www.hindawi.com/journals/bmri/2017/6274854/

Journal: BioMed Research International

Publication Date: 04/2017

Summary: L-Carnitine treatment is effective for CHF patients in improving clinical symptoms and cardiac functions, decreasing serum levels of BNP and NT-proBNP.

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Taurine Supplementation Improves Functional Capacity, Myocardial Oxygen Consumption, and Electrical Activity in Heart Failure

URL: https://www.tandfonline.com/doi/full/10.1080/19390211.2016.1267059?src=recsys

Journal: Journal of Dietary Supplements

 Publication Date: 01/2017

Summary: Our results also suggest that the short-term taurine supplementation is an effective strategy for improving some selected hemodynamic parameters in heart failure patients. Together, these findings support the view that taurine improves cardiac function and functional capacity in patients with heart failure. This idea warrants further study.

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Total red meat intake of ≥0.5 servings/d does not negatively influence cardiovascular disease risk factors: a systemically searched meta-analysis of randomized controlled trials.

URL: https://www.ncbi.nlm.nih.gov/pubmed/27881394

Journal: American Journal of Clinical Nutrition

 Publication Date: 01/2017

Summary: The results from this systematically searched meta-analysis of RCTs support the idea that the consumption of ≥0.5 servings of total red meat/d does not influence blood lipids and lipoproteins or blood pressures.

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The association of lean and fat mass with all-cause mortality in older adults: The Cardiovascular Health Study

URL: https://www.sciencedirect.com/science/article/abs/pii/S0939475316301016

Journal: Nutrition, Metabolism and Cardiovascular Diseases

 Publication Date: 11/2016

 Summary: Greater lean tissue mass is associated with improved cardiovascular and overall mortality in the elderly. The lowest levels of fat tissue mass are linked with adverse prognosis, but the highest levels show no significant mortality protection. Prevention efforts in the elderly frail may be best targeted toward improvements in lean muscle mass.

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Lipid paradox in acute myocardial infarction-the association with 30-day in-hospital mortality

URL: https://www.ncbi.nlm.nih.gov/pubmed/25738856

Journal: Critical Care Medicine

 Publication Date: 06/2015

Summary: Low low-density lipoprotein cholesterol, low triglycerides, and high Killip severity were associated with significantly higher 30-day in-hospital mortality in patients presenting with acute myocardial infarction.

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Exploring the background to the cholesterol hypothesis utilizing data obtained mainly from Japan

URL: https://www.karger.com/Article/Pdf/381654

Journal: Ann Nutr Metab

Publication Date: 04/2015

Summary: Comprehensive review of Cholesterol-heart disease hypothesis, focusing on Japan. The cholesterol hypothesis relies on very weak data—and sometimes considerably distorted data. Indeed, many studies in Japan actually show that cholesterol plays a very positive role in health.

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Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults

URL: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1819573

Journal: JAMA Internal Medicine

Publication Date: 04/2014

Summary: Results from NHANES database. Most US adults consume more added sugar than is recommended for a healthy diet. We observed a significant relationship between added sugar consumption and increased risk for CVD mortality.

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Is the use of cholesterol in mortality risk algorithms in clinical guidelines valid? Ten years prospective data from the Norwegian HUNT 2 study

URL: https://www.ncbi.nlm.nih.gov/pubmed/21951982

Journal: Journal of Evaluation Clinical Practice

 Publication Date: 02/2012

Summary: Our study provides an updated epidemiological indication of possible errors in the CVD risk algorithms of many clinical guidelines. If our findings are generalizable, clinical and public health recommendations regarding the ‘dangers’ of cholesterol should be revised. This is especially true for women, for whom moderately elevated cholesterol (by current standards) may prove to be not only harmless but even beneficial.