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Effects of a 12-Week Very-Low Carbohydrate High-Fat Diet on Maximal Aerobic Capacity, High-Intensity Intermittent Exercise, and Cardiac Autonomic Regulation: Non-randomized Parallel-Group Study

URL: https://www.frontiersin.org/articles/10.3389/fphys.2019.00912/full

Journal: Frontiers in Physiology

 Publication Date: 07/2019

 Summary: The 12 week VLCHF diet did not impair high-intensity continuous or intermittent exercise lasting up to 25 min, nor did it impair maximal cardiorespiratory performance or autonomic nervous system (ANS) activity.

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Effects of a 12-Week Very-Low Carbohydrate High-Fat Diet on Maximal Aerobic Capacity, High-Intensity Intermittent Exercise, and Cardiac Autonomic Regulation: Non-randomized Parallel-Group Study

URL: https://www.frontiersin.org/articles/10.3389/fphys.2019.00912/full#F4

Journal: Fronteirs in Physiology

 Publication Date: 07/2019

 Summary: Study of 24 healthy males on a 12 week VLCHF diet vs standard diet. The 12 week VLCHF diet did not impair high-intensity continuous or intermittent exercise lasting up to 25 min, nor did it impair maximal cardiorespiratory performance or autonomic nervous system (ANS) activit

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Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss

URL: https://insight.jci.org/articles/view/128308

Journal: JCI Insight

Publication Date: 06/2019

 Summary: Obese subjects cycled through 4 weeks each of a low, medium and high carb diet. Consistent with the perspective that MetS is a pathologic state that manifests as dietary carbohydrate intolerance, these results show that compared with eucaloric high-carbohydrate intake, LC/high-fat diets benefit MetS independent of whole-body or fat mass.

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Coronary Heart Disease and Dietary Carbohydrate, Glycemic Index, and Glycemic Load: Dose-Response Meta-analyses of Prospective Cohort Studies

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410335/

Journal: Mayo Clinic Proceedings: Innovations, Quality and Outcomes.

 Publication Date: 03/2019

 Summary: Strong and probably causal CHD-GL and GI RRs exist within populations. The RRs were remarkably higher across global exposures. The results support the consideration of these markers of carbohydrate food quality in dietary guidelines for general populations.

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Carbotoxicity—Noxious Effects of Carbohydrates

URL: https://www.sciencedirect.com/science/article/pii/S0092867418309723?via%3Dihub

Journal: Cell

Publication Date: 10/2018

 Summary: We discuss the molecular, cellular, and neuroendocrine mechanisms that link exaggerated carbohydrate intake to disease and accelerated aging as we outline dietary and pharmacologic strategies to combat carbotoxicity.

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Remission of pre-diabetes to normal glucose tolerance in obese adults with high protein versus high carbohydrate diet: randomized control trial

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093372/?fbclid=IwAR0FS5XHXENG3-VpU3cqB4RasjvBfjMKHklJSnZDg4a6Ud0UyETsM4qBnKU

Journal: BMJ Open Diabetes Research and Care

Publication Date: 09/2016

 Summary: This is the first dietary intervention feeding study, to the best of our knowledge, to report 100% remission of pre-diabetes with a HP diet and significant improvement in metabolic parameters and anti-inflammatory effects compared with a HC diet at 6 months.

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Long-Term Effects of a Very Low Carbohydrate Compared With a High Carbohydrate Diet on Renal Function in Individuals With Type 2 Diabetes: A Randomized Trial

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/26632754/

Journal: Medicine

Publication Date: 11/2015

 Summary: Compared with a traditional HC weight loss diet, consumption of an LC high protein diet does not adversely affect clinical markers of renal function in obese adults with T2DM and no preexisting kidney disease.

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Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults

URL: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1819573

Journal: JAMA Internal Medicine

Publication Date: 04/2014

Summary: Results from NHANES database. Most US adults consume more added sugar than is recommended for a healthy diet. We observed a significant relationship between added sugar consumption and increased risk for CVD mortality.

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Comparative effects of low-carbohydrate high-protein versus low-fat diets on the kidney

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/22653255/

Journal: CJASN

 Publication Date: 07/2012

Summary: In healthy obese individuals, a low-carbohydrate high-protein weight-loss diet over 2 years was not associated with noticeably harmful effects on GFR, albuminuria, or fluid and electrolyte balance compared with a low-fat diet.

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Nutrition and Alzheimer’s disease: The detrimental role of a high carbohydrate diet

URL: https://people.csail.mit.edu/seneff/EJIM_PUBLISHED.pdf

Journal: European Journal of Internal Medicine

 Publication Date: 04/2011

 Summary: A review of the role of an excess of dietary carbohydrates and deficiency of dietary fats and cholesterol in the devlopment of Alzheimer’s disease.