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Menaquinone-4 Suppresses Lipopolysaccharide-Induced Inflammation in MG6 Mouse Microglia-Derived Cells by Inhibiting the NF-κB Signaling Pathway

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540242/

Journal: International Journal of Molecular Sciences

 Publication Date: 05/2019

 Summary: Alzheimer’s disease is associated with glial inflammation. In a rat model, MK-4, a subtype of Vitamin K2, reduced the inflammatory response of glial cells to LPS exposure.

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Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer’s disease: A case study

URL: https://www.sciencedirect.com/science/article/abs/pii/S1871402118306684?via%3Dihub

Journal: Diabetes & Metabolic Syndrome: Clinical Research & Reviews

 Publication Date: 03/2019

Summary: The significant results in both MetS biomarkers and the MoCA score suggest that a ketogenic diet may serve to rescue cognition in patients with mild AD. The results of this case study are particularly compelling for ApoE4 positive (ApoE4+) subjects as ketogenic protocols extend hope and promise for AD prevention.

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Nutrition and Alzheimer’s disease: The detrimental role of a high carbohydrate diet

URL: https://people.csail.mit.edu/seneff/EJIM_PUBLISHED.pdf

Journal: European Journal of Internal Medicine

 Publication Date: 04/2011

 Summary: A review of the role of an excess of dietary carbohydrates and deficiency of dietary fats and cholesterol in the devlopment of Alzheimer’s disease.